HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 4-carboxycinnamate → 4-(3-Methoxy-3-oxopropyl)benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 4-carboxycinnamate | HCID 54440358 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 4-(3-Methoxy-3-oxopropyl)benzoic acid | HCID 11310294 | 85.8% |
Reaction Steps
A mixture of methyl 4-carboxycinnamate (1.5 g) and 10% palladium on carbon (300 mg) in methanol (5 ml) was stirred for 2 hours at ambient temperature under hydrogen atmosphere. Insoluble material was filtered off, and the filtrate was concentrated in vacuo to give 4-[2-(methoxycarbonyl)ethyl]benzoic acid (1.3 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06344462B1 |
| Source dataset | uspto-grants-2002_02 |
| ORD ID | ord-39101ccc26eb47b0a0ac0d45b7c694ec |
| Source note | uspto-grants-2002_02 |