HCID 18321072, compound → HCID 13338870, compound

HRID 1699245Notes

Reaction equation

HRID 1699245 reaction equation
C1(C[N:8]2[CH2:13][CH2:12][CH:11]([N:14]3[C:23](=[O:24])[C:22]4[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=4)[NH:16][C:15]3=[O:25])[CH2:10][CH2:9]2)C=CC=CC=1>[Pd]>[NH:8]1[CH2:9][CH2:10][CH:11]([N:14]2[C:23](=[O:24])[C:22]3[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=3)[NH:16][C:15]2=[O:25])[CH2:12][CH2:13]1

Participants

3

Reactant 1

HCID 18321072HCID 18321072, compound

Product 1

HCID 13338870HCID 13338870, compoundYield 70%

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

Prepared analogously to Example A3f) from 3-[1-(phenylmethyl)-4-piperidinyl]-2,4(1H,3H)-quinazolindione by hydrogenolysis in the presence of palladium/charcoal in a yield of 70% of theory.

Sources & evidence

ORD record
ord-ef4ae254e374463888ee86edd664a1d4
Source dataset
uspto-grants-2002_02
Patent number
US06344449B1

Reaction notes

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