HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hexahydro-1-methyl-4-[1-(phenylmethyl)-4-piperidinyl]-1H-1,4-diazepine → Hexahydro-1-methyl-4-(4-piperidinyl)-1H-1 4-diazepine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hexahydro-1-methyl-4-[1-(phenylmethyl)-4-piperidinyl]-1H-1,4-diazepine | HCID 18321160 | — |
| Catalyst | Palladium hydroxide | HCID 9942167 | — |
| Product | Hexahydro-1-methyl-4-(4-piperidinyl)-1H-1 4-diazepine | HCID 18321176 | — |
Reaction Steps
Prepared analogously to Example A3f) from hexahydro-1-methyl-4-[1-(phenylmethyl)-4-piperidinyl]-1H-1,4-diazepine by hydrogenolysis but using Pearlman's catalyst instead of palladium/charcoal, in a quantitative yield. Colourless viscous oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06344449B1 |
| Source dataset | uspto-grants-2002_02 |
| ORD ID | ord-76893da414004b26bf1c256909a01be2 |
| Source note | uspto-grants-2002_02 |