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HRID1699278

反应详情

EQUATION

反应方程式

HRID 1699278 的结构方程式

REACTANTS

反应物

3
结构：CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F
HCID2733207

O-(Benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium tetrafluoroborate

C11H16BF4N5O

结构：c1cc(N2CCNCC2)ncn1
HCID18321137

4-(Piperazin-1-yl)pyrimidine

C8H12N4

结构：CC(C)(C)OC(=O)N[C@H](Cc1cc(Br)c(N)c(Br)c1)C(=O)O
HCID21023499

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)N[C@H](Cc1cc(Br)c(N)c(Br)c1)C(=O)N1CCN(c2ccncn2)CC1
HCID68855915

未命名化合物

收率 92%

PROCEDURE

实验过程

Prepared analogously to Example A15a) from 4-amino-3,5-dibromo-N-(1,1-dimethylethoxycarbonyl)-D-phenylalanine and 1-(4-pyrimidinyl)piperazine in the presence of TBTU in a yield of 92% of theory. Colourless, amorphous substance, Rf=0.42 (FM4; Macherey-Nagel POLYGRAM® SIL G/UV254, ready-made films for TLC).