Trifluoroacetic acid → HCID 18319546, compound

Participants

Reaction Steps

To a solution of ethyl 9-[(E)-(2-tert-butoxycarbonylvinyl)]-2,3-dihydro-1-benzoxepin-4-carboxylate (0.56 g) was added trifluoroacetic acid (0.63 ml) at 0° C. The reaction mixture was stirred overnight at ambient temperature and evaporated in vacuo. The residue was triturated with diisopropyl ether to give a solid of ethyl 9-[(E)-(2-carboxyvinyl)]-2,3-dihydro-1-benzoxepin-4-carboxylate (0.3 g).

Provenance & Evidence