HCID 18319561, compound → HCID 18319618, compound

Participants

Reaction Steps

A mixture of ethyl 3-benzyloxy-2-(3-ethoxycarbonylpropyloxy)benzoate (2.5 g) and palladium on charcoal (0.25 g) in ethanol (12.5 ml) was hydrogenated under hydrogen atmosphere. The catalyst was filtered off. The filtrate was evaporated in vacuo. The residue was purified by silica gel column chromatography using a mixture of ethyl acetate and n-hexane (1:3) to give colorless oil of ethyl 3-hydroxy-2-(3-ethoxycarbonylpropyloxy)benzoate (1.86 g).

Provenance & Evidence