Nitric Acid → HCID 18319578, compound

Participants

Reaction Steps

Methyl 2,3-dihydro-7-chloro-1-benzoxepin-4-carboxylate (1.0 g) was added to nitric acid (4.5 ml, d=1.42) under ice-cooling and the mixture was stirred at ambient temperature for 2 hours. The mixture was poured into water and the isolated precipitate was collected by filtration to give methyl 2,3-dihydro-7-chloro-9-nitro-1-benzoxepin-4-carboxylate (1.04 g).

Provenance & Evidence