Ethanol → HCID 69842496, compound

Participants

Reaction Steps

(R)-2-(1H-Benzimidazol-2-yl)-4′-[4-[2-[N-benzyl-N-(2-hydroxy-2-phenylethyl)amino]ethyl]phenyl]acetanilide (240 mg) was dissolved in 30 ml of ethanol, then 170 mg of 10% palladium-carbon was added thereto and the mixture was stirred for nine hours in a hydrogen atmosphere under atmospheric pressure. The catalyst was filtered off, the solvent was evaporated in vacuo, and the residue was washed with ethanol-ethyl acetate to give 200 mg of (R)-2-(1H-benzimidazol-2-yl)-4′-[2-[(2-hydroxy-2-phenylethyl)amino]-ethyl]acetanilide.

Provenance & Evidence