HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyrrole → 6-(1-Pyrrolyl)-1-(dimethylamino)indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyrrole | HCID 8027 | — |
| Reactant | Carbonic acid, rubidium salt (1:2) | HCID 11431 | — |
| Reactant | Tris(1,1-dimethylethyl)phosphine | HCID 83681 | — |
| Reactant | 2,4-dichlorophenylacetaldehyde N,N-dimethylhydrazone | HCID 54340331 | — |
| Product | 6-(1-Pyrrolyl)-1-(dimethylamino)indole | HCID 9837446 | — |
Reaction Steps
6-(1-pyrrolyl)-1-(dimethylamino)indole was prepared in the same manner as in Example 12 except that 2,4-dichlorophenylacetaldehyde N,N-dimethylhydrazone was used in place of 2,6-dichlorophenylacetaldehyde N,N-dimethylhydrazone, tri(t-butyl)phosphine was used in place of 1-(N,N-dimethylaminomethyl)-2-(di-t-butylphosphino)ferrocene, pyrrole was used in place of piperazine, and rubidium carbonate was used in place of t-butoxysodium. (Yield: 2′%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06346621B1 |
| Source dataset | uspto-grants-2002_02 |
| ORD ID | ord-8511c3906ead47c0b5b48f6ff16ac832 |
| Source note | uspto-grants-2002_02 |