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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1699471Generated: November 1, 2026

3,5-Bis(trifluoromethyl)benzoyl chloride → HCID 131722250, compound

https://huagongshe.com/reaction/1699471

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,5-Bis(trifluoromethyl)benzoyl chlorideHCID 101856—
ReactantHCID 131722251HCID 131722251—
ProductHCID 131722250HCID 131722250—

Reaction Steps

Using the same reaction procedure as described in example B5, 3,5-bis(trifluoromethyl)benzoyl chloride was reacted with intermediate 8 to form (±)-trans-1-[3,5-bis(trifluoromethyl)benzoyl]-4-[4-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl]-2-(phenylmethyl)piperidine (compound 43, mp. 156.1° C.).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06346540B1
Source datasetuspto-grants-2002_02
ORD IDord-497e4528199a4099b16d34a8f9f31bfb
Source noteuspto-grants-2002_02