Diisopropylethylamine → HCID 18320690, compound

Participants

Reaction Steps

A solution of 57 mg (0.25 mmol) of the product of step c) in 5 ml of benzene was heated to 95° C. for 5 hours. After cooling to room temperature the benzene solution was rapidly added to a freshly prepared suspension of 120 mg (0.24 mmol) of the product of step b) and 31 mg (0.24 mmol) of ethyldiisopropylamine in 10 ml of THF. The resulting solution was stirred for 2 hours. The solvents were evaporated and the residue suspended in 20 ml of water and stirred for 10 minutes. The product was filtered and dried, giving 130 mg (84%) of the sub-title compound as a yellowish solid.

Provenance & Evidence