HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1699534Generated: November 1, 2026
Triphenylphosphine → HCID 69952084, compound
https://huagongshe.com/reaction/1699534
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Triphenylphosphine | HCID 11776 | — |
| Reactant | Lithium Chloride | HCID 433294 | — |
| Reactant | Phthalimide potassium salt | HCID 24194345 | — |
| Reactant | HCID 69952465 | HCID 69952465 | — |
| Catalyst | Bis(dibenzylideneacetone)palladium | HCID 9811564 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 69952084 | HCID 69952084 | 57.1% |
Reaction Steps
In a flask was added 0.064 g (0.10 mmole) of the product obtained in step b), 0.046 g (0.25 mmole) of potassium phthalimide, 0.0096 g (0.01 mmole) of Pd2(dba)3, 0.013 g (0.05 mmole) of triphenylphosphine, 1 mg of lithium chloride and finally 7 ml of dry DMF. The flask was sealed and stirred under nitrogen at 70° C. under nitrogen for 90 minutes. The mixture was partitioned between EtOAc and water, and the organic phase was collected and concentrated. The residue was purified on silica (Heptane:EtOAc 1:3), giving 0.040 g (55%) of the sub-title compound as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06346625B1 |
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| Source dataset | uspto-grants-2002_02 |
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| ORD ID | ord-4b3be7156d544783beb57e472f1c16bb |
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| Source note | uspto-grants-2002_02 |
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