HCID 54011725, compound → HCID 18680862, compound

HRID 1699645Notes

Reaction equation

HRID 1699645 reaction equation
[CH2:1]([O:3][C:4]([C:6]1[CH:7]=[CH:8][C:9]2[N:13]=[C:12]([CH3:14])[N:11]([CH2:15][C:16]3[CH:21]=[CH:20][C:19]([CH:22]=[CH:23][C:24]4[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=4)=[CH:18][CH:17]=3)[C:10]=2[CH:30]=1)=[O:5])[CH3:2]>[C].[Pd].C(O)C>[CH2:1]([O:3][C:4]([C:6]1[CH:7]=[CH:8][C:9]2[N:13]=[C:12]([CH3:14])[N:11]([CH2:15][C:16]3[CH:21]=[CH:20][C:19]([CH2:22][CH2:23][C:24]4[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=4)=[CH:18][CH:17]=3)[C:10]=2[CH:30]=1)=[O:5])[CH3:2]

Participants

4

Reactant 1

HCID 54011725HCID 54011725, compound

Product 1

HCID 18680862HCID 18680862, compound

Reagents, catalysts & solvents 2

HCID 178418390HCID 178418390, compoundCatalystHCID 702EthanolSolvent

Procedure

In a nitrogen environment, 5% palladium-carbon is added to an ethanol (910 ml) solution of 6-ethoxycarbonyl-2-methyl-1-[4-(2-phenylethenyl)benzyl]benzimidazole (0.320 g). The solution is stirred for 23 hours under a nitrogen environment. Solids are separated through filtration, the filtrate is concentrated, and thus, 6-ethoxycarbonyl-2-methyl-1-[4-(2-phenylethyl)benzyl]-benzimidazole is obtained. This material is immediately used for the following reaction.

Workup

  1. customSolids are separated through filtration
  2. concentrationthe filtrate is concentrated

Sources & evidence

ORD record
ord-550011531ace45f48eddd586b040ba11
Source dataset
uspto-grants-2002_02
Patent number
US06348032B1

Reaction notes

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