反应详情

A composition suitable for administration in vaginal suppository form la prepared by weighing 2 mg of finely divided polynucleotide medicinal substance into a tared container, adding 10 ml of 0.5% bupivacaine HCl in purified water, to make a total of 10 g, and dissolving or mixing depending on the solubility of the medicinal substance; 70 g of glycerin is added and mixed; 20 g of granular gelatin is then added and the composition heated carefully on a steam bath until the gelatin is dissolved. The melted mixture is poured into chilled molds to yield 20 vaginal suppositories of 6 grams each containing 100 mcg of polynucleotide medicinal substance in admixture with 2.5 mg bupivacaine.

1. customA composition suitable for administration in vaginal suppository form la prepared
2. dissolutiondissolving
3. additionmixing
4. additionmixed
5. addition20 g of granular gelatin is then added
6. temperaturethe composition heated carefully on a steam bath until the gelatin
7. dissolutionis dissolved
8. additionThe melted mixture is poured
9. temperatureinto chilled molds