HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Bromo-2-methylpropane → 6-(3-fluoro-4-methoxyphenyl)-2-isobutyl-5-(4-methoxyphenyl)-2H-pyridazin-3-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Bromo-2-methylpropane | HCID 6555 | — |
| Reactant | 6-(3-fluoro-4-methoxyphenyl)-5-(4-methoxyphenyl)-2H-pyridazin-3-one | HCID 18369367 | — |
| Product | 6-(3-fluoro-4-methoxyphenyl)-2-isobutyl-5-(4-methoxyphenyl)-2H-pyridazin-3-one | HCID 17797527 | 91.3% |
Reaction Steps
Using 6-(3-fluoro-4-methoxyphenyl)-5-(4-methoxyphenyl)-2H-pyridazin-3-one and isobutyl bromide as starting materials, the procedures of Example 146 were repeated likewise, whereby the title compound was obtained in a yield of 91.3%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06348468B1 |
| Source dataset | uspto-grants-2002_02 |
| ORD ID | ord-d9fe8f96fe4d47c6b5dd08ab468143ba |
| Source note | uspto-grants-2002_02 |