HuagongsheHuagongshe Chemistry Print Report · For research reference only
(Chloromethyl)cyclopropane → 2-cyclopropylmethyl-6-(3-fluoro-4-methoxyphenyl)-5-(4-methoxyphenyl)-2H-pyridazin-3-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (Chloromethyl)cyclopropane | HCID 80013 | — |
| Reactant | 6-(3-fluoro-4-methoxyphenyl)-5-(4-methoxyphenyl)-2H-pyridazin-3-one | HCID 18369367 | — |
| Product | 2-cyclopropylmethyl-6-(3-fluoro-4-methoxyphenyl)-5-(4-methoxyphenyl)-2H-pyridazin-3-one | HCID 18369353 | 93% |
Reaction Steps
Using 6-(3-fluoro-4-methoxyphenyl)-5-(4-methoxyphenyl)-2H-pyridazin-3-one and (chloromethyl)cyclopropane as starting materials, the procedures of Example 146 were repeated likewise, whereby the title compound was obtained in a yield of 93.0%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06348468B1 |
| Source dataset | uspto-grants-2002_02 |
| ORD ID | ord-9e8e60cd6cff43d6aed7715f917acb91 |
| Source note | uspto-grants-2002_02 |