HCID 18369307, compound → HCID 53730249, compound

HRID 1699783Notes

Reaction equation

HRID 1699783 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([C:10]2[C:15]([C:16]3[CH:21]=[CH:20][C:19]([O:22][CH3:23])=[CH:18][CH:17]=3)=[N:14][NH:13][C:12](=[O:24])[CH:11]=2)[CH:5]=[CH:6][C:7]=1[O:8][CH3:9].[Cl:25][C:26]1[CH:35]=[CH:34][C:29]([CH:30]=[CH:31][CH2:32]Cl)=[CH:28][CH:27]=1>>[Cl:25][C:26]1[CH:35]=[CH:34][C:29]([CH:30]=[CH:31][CH2:32][N:13]2[C:12](=[O:24])[CH:11]=[C:10]([C:4]3[CH:5]=[CH:6][C:7]([O:8][CH3:9])=[C:2]([F:1])[CH:3]=3)[C:15]([C:16]3[CH:17]=[CH:18][C:19]([O:22][CH3:23])=[CH:20][CH:21]=3)=[N:14]2)=[CH:28][CH:27]=1

Participants

3

Reactant 2

HCID 18369307HCID 18369307, compoundHCID 53728250p-Chlorocinnamyl chloride

Product 1

HCID 53730249HCID 53730249, compoundYield 58.7%

Procedure

Using 5-(3-fluoro-4-methoxyphenyl)-6-(4-methoxyphenyl)-2H-pyridazin-3-one and 4-chlorocinnamyl chloride as starting materials, the procedures of Example 12 were repeated likewise, whereby the title compound was obtained in a yield of 58.7%.

Sources & evidence

ORD record
ord-71456187db8b4bd18f5e155365bdcc7f
Source dataset
uspto-grants-2002_02
Patent number
US06348468B1

Reaction notes

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