Isobutyl iodide → HCID 17797536, compound

HRID 1699785Notes

Reaction equation

[F:1][C:2]1[CH:3]=[C:4]([C:10]2[C:15]([C:16]3[CH:21]=[CH:20][C:19]([O:22][CH3:23])=[CH:18][CH:17]=3)=[N:14][NH:13][C:12](=[O:24])[CH:11]=2)[CH:5]=[CH:6][C:7]=1[O:8][CH3:9].[CH2:25](I)[CH:26]([CH3:28])[CH3:27]>>[F:1][C:2]1[CH:3]=[C:4]([C:10]2[C:15]([C:16]3[CH:17]=[CH:18][C:19]([O:22][CH3:23])=[CH:20][CH:21]=3)=[N:14][N:13]([CH2:25][CH:26]([CH3:28])[CH3:27])[C:12](=[O:24])[CH:11]=2)[CH:5]=[CH:6][C:7]=1[O:8][CH3:9]

Participants

Reactant 2

HCID 10556Isobutyl iodide

HCID 18369307HCID 18369307, compound

Product 1

HCID 17797536HCID 17797536, compoundYield 75.1%

Procedure

Using 5-(3-fluoro-4-methoxyphenyl)-6-(4-methoxyphenyl)-2H-pyridazin-3-one and isobutyl iodide as starting materials, the procedures of Example 146 were repeated likewise, whereby the title compound was obtained in a yield of 75.1%.

Sources & evidence

ORD record: ord-b798ea8d2ac34027b82cd9529395a000
Source dataset: uspto-grants-2002_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06348468B1

Reaction notes

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