Isobutyl iodide → HCID 18369381, compound

HRID 1699790Notes

Reaction equation

[F:1][C:2]1[CH:3]=[C:4]([C:10]2[C:15]([C:16]3[CH:21]=[CH:20][C:19]([O:22][CH3:23])=[C:18]([F:24])[CH:17]=3)=[N:14][NH:13][C:12](=[O:25])[CH:11]=2)[CH:5]=[CH:6][C:7]=1[O:8][CH3:9].[CH2:26](I)[CH:27]([CH3:29])[CH3:28]>>[F:1][C:2]1[CH:3]=[C:4]([C:10]2[C:15]([C:16]3[CH:21]=[CH:20][C:19]([O:22][CH3:23])=[C:18]([F:24])[CH:17]=3)=[N:14][N:13]([CH2:26][CH:27]([CH3:29])[CH3:28])[C:12](=[O:25])[CH:11]=2)[CH:5]=[CH:6][C:7]=1[O:8][CH3:9]

Participants

Reactant 2

HCID 10556Isobutyl iodide

HCID 18369405HCID 18369405, compound

Product 1

HCID 18369381HCID 18369381, compound

Procedure

Using 5,6-bis(3-fluoro-4-methoxyphenyl)-2H-pyridazin-3-one and isobutyl iodide as starting materials, the procedures of Example 146 were repeated likewise, whereby the title compound was obtained quantitatively.

Sources & evidence

ORD record: ord-d8c92e33591441cc97f637e9e6158ec6
Source dataset: uspto-grants-2002_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06348468B1

Reaction notes

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