Water → HCID 22388428, compound

Participants

Reaction Steps

A mixture of diethyl 2-methylpyrazolo[1,5-a]pyridine-3,5-dicarboxylate (100 mg), a 50% aqueous sodium hydroxide solution (160 mg), water (0.5 ml) and ethanol (1.0 ml) was refluxed under heating for 30 min. Then, the reaction mixture was adjusted to pH 4 under ice-cooling and stirred at the same temperature for 30 min. The precipitate was collected by filtration and washed with water to give the objective compound (50 mg) as a pale-brown powder.

Provenance & Evidence