HCID 22388201, compound → 3H-Imidazo[4,5-b]pyridine-5-carbonitrile, 2-methyl-

HRID 1699818Notes

Reaction equation

HRID 1699818 reaction equation
[CH3:1][C:2]1[N:12](CC2C=CC(C3C=CC=CC=3)=CC=2)[C:5]2=[N:6][C:7]([C:10]#[N:11])=[CH:8][CH:9]=[C:4]2[N:3]=1.CC1N(CC2C=CC(C3C=CC=CC=3)=CC=2)C2C(N=1)=NC(C#N)=CC=2>>[CH3:1][C:2]1[NH:3][C:4]2[C:5]([N:12]=1)=[N:6][C:7]([C:10]#[N:11])=[CH:8][CH:9]=2

Participants

3

Reactant 2

HCID 22388201HCID 22388201, compoundHCID 22388241HCID 22388241, compound

Product 1

HCID 223881363H-Imidazo[4,5-b]pyridine-5-carbonitrile, 2-methyl-Yield 293%

Procedure

In the same manner as in the following Preparation Example 14-2, 2-methyl-3-(4-phenylbenzyl)-3H-imidazo[4,5-b]pyridine-5-carbonitrile (140 mg) and 2-methyl-1-(4-phenylbenzyl)-1H-imidazo[4,5-b]pyridine-5-carbonitrile (113 mg) were respectively obtained as pale-brown crystals and pale-yellow amorphous from 2-methyl-1H-imidazo[4,5-b]pyridine-5-carbonitrile (200 mg).

Sources & evidence

ORD record
ord-4ae825a1701248a6942ccb4852801a80
Source dataset
uspto-grants-2002_02
Patent number
US06348474B1

Reaction notes

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