HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuric Acid → HCID 18370049, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | Toluene | HCID 1140 | — |
| Reactant | (+-)-2-Butanol | HCID 6568 | — |
| Reactant | HCID 18370034 | HCID 18370034 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 18370049 | HCID 18370049 | — |
Reaction Steps
The mixture of 2.0 gr DL-N benzensulfonyl-3 aminobutyric acid (I), 1.0 gr 2-butanol, 30 ml toluene and 0.04 gr H2SO4 (conc) was heated under reflux for ca 6 hr. The water formed in the reaction was separated by azeotropic distillation. The cooled reaction mixture was washed twice with bicarbonate 2%, and dried over magnesium sulfate. Distillation of the solvent and alcohol yield 1.8 gr procuct, confirmed by spectroscopy.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06348614B1 |
| Source dataset | uspto-grants-2002_02 |
| ORD ID | ord-f012774e20fd4cefba5765341c5f857b |
| Source note | uspto-grants-2002_02 |