HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → 3-Chlorocarbonyl-propionic acid 3,7-dimethyl-oct-6-enylester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 4-[(3,7-Dimethyloct-6-en-1-yl)oxy]-4-oxobutanoic acid | HCID 11172890 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 3-Chlorocarbonyl-propionic acid 3,7-dimethyl-oct-6-enylester | HCID 15390723 | 82.8% |
Reaction Steps
A solution of 35.5 g succinic acid mono-(3,7-dimethyl-oct-6-enyl) ester and 12.3 g pyridine in 200 ml of ether was cooled in an ice bath. Then a solution of 18.0 g thionyl chloride in 100 ml of ether was added dropwise at 5-10° C. during 90 min. The resulting solution was stirred overnight at room temperature, then it was filtered and evaporated to dryness. The residue was not further purified to yield 31.5 g of a yellow liquid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06348618B1 |
| Source dataset | uspto-grants-2002_02 |
| ORD ID | ord-f2cfeb45e6184c41b2047a00a8b2b4ac |
| Source note | uspto-grants-2002_02 |