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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1700042Generated: November 1, 2026

Ethyl chloroformate → 3-Butenoic acid, 2-oxo-4-phenyl-, ethyl ester

https://huagongshe.com/reaction/1700042

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl chloroformateHCID 10928—
Reactant2-Oxo-4-phenylbut-3-enoic acidHCID 243435—
Product3-Butenoic acid, 2-oxo-4-phenyl-, ethyl esterHCID 3850341—

Reaction Steps

Furthermore, the pyruvic acid compound (I) can also be produced, for example, in accordance with: (1) the process in which benzaldehyde and sodium pyruvate are condensed together to give benzalpyruvic acid, and the benzalpyruvic acid is then reacted with ethyl chloroformate to give ethyl benzalpyruvate, and the ethyl benzalpyruvate is then reduced [EP387058]; or (2) the process in which phenetyl bromide is reacted with carbon monoxide in the presence of a cobalt carbonyl catalyst [J. Mol. Cat., 88, 295(1994)]. The process for producing the pyruvic acid compound (I) as the starting material is not limited to these processes, either of which can be used as the production process for the starting material in the present invention.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06348617B1
Source datasetuspto-grants-2002_02
ORD IDord-2ff0e57686424179b23529128b5429b5
Source noteuspto-grants-2002_02