Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Aminoglutethimide | HCID 2145 | — |
| Reactant | 8-Dimethylamino-methylene-6,8-dihydro-1-thia-3,6diaza-as-indacen-7one | HCID 86585523 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | HCID 178435252 | HCID 178435252 | 54% |
Reaction Steps
A mixture of 8-dimethylamino-methylene-6,8-dihydro-1-thia-3,6-diaza-as-indacen-7-one (Procedure E, 0.040 g, 0.163 mmol), DL-aminoglutethimide (0.055 g, 0.237 mmol) in absolute ethanol (5 ml) was heated with stirring at 90° C. for 16 h. The reaction was diluted with ethanol and diethyl ether and the product collected by filtration to yield 0.038 g (54%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06350747B1 |
|---|
| Source dataset | uspto-grants-2002_02 |
|---|
| ORD ID | ord-6d976f46b92244b497a1625113797ff8 |
|---|
| Source note | uspto-grants-2002_02 |
|---|
