HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1700155Generated: October 26, 2026
3-Fluorophenylhydrazine hydrochloride → 8-[2-(3-fluorophenyl)hydrazinyl]pyrrolo[2,3-g][1,3]benzothiazol-7-one
https://huagongshe.com/reaction/1700155
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 3-Fluorophenylhydrazine hydrochloride | HCID 2723914 | — |
| Reactant | 6H-thiazolo[5,4-e]indole-7,8-dione | HCID 11745756 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 8-[2-(3-fluorophenyl)hydrazinyl]pyrrolo[2,3-g][1,3]benzothiazol-7-one | HCID 178517007 | 60.2% |
Reaction Steps
6H-1-Thia-3,6-diaza-as-indacen-7,8-dione (Procedure A, 50 mg, 0.25 mmol) was combined with 3-fluorophenylhydrazine hydrochloride (50 mg, 0.3 mmol) in 2 ml of ethanol and heated at 70° C. for 6 hrs. The product was collected by filtration of the hot solution, washing with ethanol and diethyl ether, to give 47 mg (60%) of the title compound as a brown solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06350747B1 |
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| Source dataset | uspto-grants-2002_02 |
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| ORD ID | ord-0a6edc3368684b8f86345a2681923d4e |
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| Source note | uspto-grants-2002_02 |
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