HRID1700263

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：COC(=O)[C@H]1[C@@H](c2ccc(C)cc2)C[C@@H]2CC[C@H]1N2C

HCID125416

[1R-(exo,exo)]-8-Methyl-3-(4-methylphenyl)-8-azabicyclo[3.2.1]octane-2-carboxylic acid methyl ester

C17H23NO2

结构：COC(=O)[C@H]1[C@@H](c2ccccc2)C[C@@H]2CC[C@H]1N2C

HCID170832

未命名化合物

PRODUCTS

生成物

结构：Cc1ccc([C@H]2C[C@@H]3CC[C@H]([C@H]2C=O)N3C)cc1

HCID10610260

未命名化合物

PROCEDURE

实验过程

Using a procedure similar to that described in Example 8, sub-part b, except replacing the compound 15 used therein with compound 16, the title compound 19 was prepared as a colorless oil: 1H NMR (CDCl3) δ1.70 (d, 1H. J=8.7 Hz), 1.60-1.78 (m, 1H), 1.89 (dt, 1H, J=3.9 and 12.9), 2.19 (s, 3H), 2.30 (s, 3H), 2.10-2.33 (m, 2H), 2.39-2.53 (m, 2H), 3.14 (dt, 1H, J=5.7 and 12.9 Hz), 3.36-3.45 (m, 1H), 3.46-3.55 (m, 1H), 7.10 (br s, 4H), 9.66 (d, 1H, J=3.3 Hz).