Acetyl chloride → HCID 18318007, compound

HRID 1700373Notes

Reaction equation

[CH:1]1([C:14]2([C:18]([OH:20])=[O:19])[CH2:17][CH2:16][CH2:15]2)[C:13]2[NH:12][C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[C:5]=2[CH2:4][CH2:3][NH:2]1.[C:21](Cl)(=[O:23])[CH3:22]>>[C:21]([N:2]1[CH2:3][CH2:4][C:5]2[C:6]3[C:11](=[CH:10][CH:9]=[CH:8][CH:7]=3)[NH:12][C:13]=2[CH:1]1[C:14]1([C:18]([OH:20])=[O:19])[CH2:15][CH2:16][CH2:17]1)(=[O:23])[CH3:22]

Participants

Reactant 2

HCID 6367Acetyl chloride

HCID 18317955HCID 18317955, compound

Product 1

HCID 18318007HCID 18318007, compound

Procedure

The procedure is as in Example 55, using as substrate the compound of Example 35 and as reagent acetyl chloride.

Sources & evidence

ORD record: ord-b6a905eaf72748e287903033ab3c84e0
Source dataset: uspto-grants-2002_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06350757B1

Reaction notes

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