HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → 1-(2-Formyl-6-chloro-2,3,4,9-tetrahydro-1H-beta-carbolin-1-yl)cyclobutanecarboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Reactant | Ethyl 1-(6-chloro-2,3,4,9-tetrahydro-1H-beta-carbolin-1-yl)cyclobutanecarboxylate Hydrochloride | HCID 18317933 | — |
| Product | 1-(2-Formyl-6-chloro-2,3,4,9-tetrahydro-1H-beta-carbolin-1-yl)cyclobutanecarboxamide | HCID 18317961 | — |
Reaction Steps
Reaction between the compound of Example 1 and aminocarbaldehyde in the presence of sodium methoxide in dimethylformamide enables the desired product to be obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06350757B1 |
| Source dataset | uspto-grants-2002_02 |
| ORD ID | ord-73254fc7f7fc48fda239f71de6616003 |
| Source note | uspto-grants-2002_02 |