Benzaldehyde → HCID 18317684, compound

Participants

Reaction Steps

A solution of 5-(2-chlorophenyl)-cyclohexane-1,3-dione (1.0 g), hydrazine hydrochloride (0.31 g) in ethanol (10 ml) was refluxed for 3 hours. To the solution was added benzaldehyde (1.5 g), and the mixture was refluxed for 4 days. Under reduced pressure, the solvent was evaporated, and the residue was purified with silica gel column chromatography to give crystals, which were recrystallized from ethyl acetate-hexane to give 6-(2-chlorophenyl)-3-phenyl-4,5,6,7-tetrahydroindazol-4-one (0.06 g) as crystals.

Provenance & Evidence