HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonium Acetate → 1-Amino-5-(2-chloro-5-methylphenyl)cyclohexen-3-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonium Acetate | HCID 517165 | — |
| Reactant | 5-(2-Chloro-5-methylphenyl)cyclohexane-1,3-dione | HCID 18317578 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 1-Amino-5-(2-chloro-5-methylphenyl)cyclohexen-3-one | HCID 18317649 | 97.1% |
Reaction Steps
A solution of 5-(2-chloro-5-methylphenyl)cyclohexane-1,3-dione (3.0 g) and ammonium acetate (2.9 g) in ethanol (50 ml) was refluxed for 13 hours. Under reduced pressure, the solvent was evaporated, and precipitated crystals were washed with water and toluene, and dried to give 1-amino-5-(2-chloro-5-methylphenyl)cyclohexen-3-one (2.9 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06350749B1 |
| Source dataset | uspto-grants-2002_02 |
| ORD ID | ord-a742a373b9f042bfab59365a24c1a2f3 |
| Source note | uspto-grants-2002_02 |