Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1700850Generated: October 31, 2026

Carbon Dioxide → 4-Chloro-2-methylbenzoic acid

https://huagongshe.com/reaction/1700850

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCarbon DioxideHCID 280—
Reactant2-Bromo-5-chlorotolueneHCID 84476—
ReactantCID 53628100HCID 178418400—
Product4-Chloro-2-methylbenzoic acidHCID 348269—

Reaction Steps

in the first stage a) according to the invention 2-bromo-5-chlorotoluene is reacted with a secondary or tertiary organolithium compound, particularly preferably sec-butyllithium, and CO2 to give the first intermediate 4-chloro-2-methylbenzoic acid,

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06350904B1
Source datasetuspto-grants-2002_02
ORD IDord-8a6f5a0ddcb24014a60ddfe4132fa3ab
Source noteuspto-grants-2002_02