Ethyl Acrylate → 3-[N-Dodecyl-N-[2-[4-iodophenoxy]ethyl]amino]propanoic Acid, Ethyl Ester

Participants

Reaction Steps

A mixture of N-2-[4-iodophenoxy]ethyldodecylamine (1.0 g, 2.3 mmol), ethyl acrylate (1.2 g, 12 mmol) and ethanol (3 ml) was stirred and refluxed for 6 h, and then concentrated in vacuo . The residue was chromatographed on silica gel (hexane/ethyl acetate 8:1) to afford the title compound (1.05 g, 86%) as a colorless oil.

Provenance & Evidence