3-Pyridinylboronic acid → 4-[4-Trifluoromethyl-6-(4-trifluoromethyl-phenyl)-pyrimidin-2-yl]-[2,3']bipyridinyl

HRID 170091Notes

Reaction equation

HRID 170091 reaction equation
[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[n:9][c:10](-[c:18]3[cH:19][cH:20][c:21]([C:24]([F:25])([F:26])[F:27])[cH:22][cH:23]3)[cH:11][c:12]([C:14]([F:15])([F:16])[F:17])[n:13]2)[cH:7]1.[n:28]1[cH:29][c:30]([B:34]([OH:35])[OH:36])[cH:31][cH:32][cH:33]1>>[c:2]1(-[c:30]2[cH:29][n:28][cH:33][cH:32][cH:31]2)[n:3][cH:4][cH:5][c:6](-[c:8]2[n:9][c:10](-[c:18]3[cH:19][cH:20][c:21]([C:24]([F:25])([F:26])[F:27])[cH:22][cH:23]3)[cH:11][c:12]([C:14]([F:15])([F:16])[F:17])[n:13]2)[cH:7]1

Participants

3

Reactant 2

HCID 27343783-Pyridinylboronic acidHCID 574687302-(2-Chloro-pyridin-4-yl)-4-trifluoromethyl-6-(4-trifluoromethyl-phenyl)-pyrimidine

Product 1

HCID 866154534-[4-Trifluoromethyl-6-(4-trifluoromethyl-phenyl)-pyrimidin-2-yl]-[2,3']bipyridinyl

Sources & evidence

ORD record
ord-affbb536263b4a1bb6c7b8222f82d80b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

Loading…