Dimethylamine → HCID 20348063, compound

Participants

Reaction Steps

To 18 parts of pyridine which has been saturated with dry gaseous dimethylamine is added dropwise 1 part of 2,6-diphenoxybenzoyl chloride in 2 parts of pyridine. The resulting mixture is stirred for 30 minutes, concentrated under reduced pressure, and poured into 54 parts of water. The mixture is made acidic with concentrated hydrochloric acid, and the solid precipitate is collected, washed with water, dried, and recrystallized first from acetonitrile and then from 1-chlorobutane to give N,N dimethyl-2,6-diphenoxybenzamide, M.P. 109°-111°.

Provenance & Evidence