Pyridine → HCID 20348115, compound

Participants

Reaction Steps

0.01 mole of 1-(2,4,6-trichlorophenyl)-3-[3-{α-(2,4-di-t-amylphenoxy)acetamido}benzamido]-4-hydroxy-5-pyrazolone and 0.01 mole of phenyl isocyanate are dissolved in 100 ml of dehydrated toluene, added with 0.02 moles of pyridine and heated for 5 to 6 hours under reflux. The solvent is eliminated under reduced pressure after the reaction, and n-hexane is added. The solid is collected by filtration, then washed with n-hexane and dried to obtain the coupler (1) in a state of colorless powder with a melting point 72°-77° C.

Provenance & Evidence