HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hexamethylenetetramine → p-(Trifluoromethoxy)benzaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hexamethylenetetramine | HCID 4101 | — |
| Reactant | 1-(Bromomethyl)-4-(trifluoromethoxy)benzene | HCID 142785 | — |
| Reactant | HCID 20348560 | HCID 20348560 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Water | HCID 962 | — |
| Product | p-(Trifluoromethoxy)benzaldehyde | HCID 69573 | — |
Reaction Steps
To a solution of hexamethylenetetramine (300 g; 2.14 mole) in ethanol (900 ml) and water (600 ml) a mixture of α-bromo-4-trifluoromethoxytoluene and α,α-dibromo-4-trifluoromethoxytoluene (300 g; 1.11 mole; 76:24 mixture) is added. The reaction mixture is stirred and heated at reflux for 3 hours under a nitrogen atmosphere, and then stirred overnight at room temperature.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04191768 |
| Source dataset | uspto-grants-1980_03 |
| ORD ID | ord-ef0783f07cd44129be8e6758487105f6 |
| Source note | uspto-grants-1980_03 |