HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclohexyl isocyanate → 1-Cyclohexyl-3-(4,5,6,7-tetrahydrobenzo[b]thien-4-yl)urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclohexyl isocyanate | HCID 18502 | — |
| Reactant | 4,5,6,7-Tetrahydrobenzo[b]thiophen-4-amine hydrochloride | HCID 17388600 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 1-Cyclohexyl-3-(4,5,6,7-tetrahydrobenzo[b]thien-4-yl)urea | HCID 20348983 | — |
Reaction Steps
In a similar manner, as described in Example 1, 4,5,6,7-tetrahydrobenzo[b]thiophen-4-amine hydrochloride is allowed to react with cyclohexyl isocyanate in dry tetrahydrofuran to afford 7 grams of 1-cyclohexyl-3-(4,5,6,7-tetrahydrobenzo[b]thien-4-yl)urea, melting point 222° C. to 225° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04191830 |
| Source dataset | uspto-grants-1980_03 |
| ORD ID | ord-c6a30b8f15b14db49eeb0e813935872a |
| Source note | uspto-grants-1980_03 |