(2R)-1-Bromo-2,6-dimethylheptane → (2R,6R)-(+)-1-tert. Butoxy-2,6,10-trimethylundecane

Participants

Reaction Steps

Reaction of the Grignard reagent, i.e., the magnesium salt of (R)-1-bromo-2,6-dimethylheptane with the (R)-(+)-4-tert. butoxy-3-methyl-1-butanol p-toluenesulfonate was carried out using the procedure described in Example 12. The desired product (2R,6R)-(+)-1-tert. butoxy-2,6,10-trimethylundecane was obtained as a colorless oil, b.p. 90° C. (bath temperature) (0.1 mm Hg.).

Provenance & Evidence