HCID 20347479, compound → HCID 20347476, compound

HRID 1701279Notes

Reaction equation

HRID 1701279 reaction equation
[NH2:1][C:2]1[CH:15]=[C:14]([Cl:16])[C:13]([Cl:17])=[CH:12][C:3]=1[CH2:4][N:5]1[CH:9]=[CH:8][CH:7]=[C:6]1[C:10]#[N:11].ClC1C(Cl)=CC2N[C:27](=O)[C:26]3=CC=[CH:32][N:25]3[CH2:24][C:23]=2C=1>>[Cl:17][C:13]1[C:14]([Cl:16])=[CH:15][C:2]2[N:1]=[C:10]([N:11]3[CH2:27][CH2:26][N:25]([CH3:32])[CH2:24][CH2:23]3)[C:6]3=[CH:7][CH:8]=[CH:9][N:5]3[CH2:4][C:3]=2[CH:12]=1

Participants

3

Reactant 2

HCID 20347479HCID 20347479, compoundHCID 20347484HCID 20347484, compound

Product 1

HCID 20347476HCID 20347476, compound

Procedure

Following the general procedure of Example 1, 1-(2-amino-4,5-dichlorobenzyl)-2-pyrrolecarbonitrile is converted to 7,8-dichloro-5,10-dihydro-11H-pyrrolo[2,1-c][1,4]benzodiazepin-11-one and thence to the title compound.

Sources & evidence

ORD record
ord-b5594c5be73e4699b91c4c5391c59d6c
Source dataset
uspto-grants-1980_03
Patent number
US04192803

Reaction notes

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