Benzocaine → HCID 43217369, compound

HRID 1701334Notes

Reaction equation

HRID 1701334 reaction equation
[NH2:1][C:2]1[CH:12]=[CH:11][C:5]([C:6]([O:8][CH2:9][CH3:10])=[O:7])=[CH:4][CH:3]=1.[Cl:13][C:14]1[S:18][C:17]([CH:19]=O)=[CH:16][CH:15]=1>>[CH2:9]([O:8][C:6](=[O:7])[C:5]1[CH:4]=[CH:3][C:2]([NH:1][CH2:19][C:17]2[S:18][C:14]([Cl:13])=[CH:15][CH:16]=2)=[CH:12][CH:11]=1)[CH3:10]

Participants

3

Reactant 2

HCID 2337BenzocaineHCID 817002-Thiophenecarboxaldehyde, 5-chloro-

Product 1

HCID 43217369HCID 43217369, compound

Procedure

4-(((5-chloro-2-thienyl)methyl)amino)benzoic acid ethyl ester was prepared from ethyl p-aminobenzoate and 5-chloro-2-thiophenecarboxaldehyde. Melting point was 108°-109° C.

Sources & evidence

ORD record
ord-f11249602afd47e19454372965942672
Source dataset
uspto-grants-1980_03
Patent number
US04192884

Reaction notes

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