HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1701335Generated: October 31, 2026
1-Pyrrolidineethanamine → 9H-Fluorene-9-carboxamide, N-(2-(1-pyrrolidinyl)ethyl)-, hydrochloride (1:1)
https://huagongshe.com/reaction/1701335
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1-Pyrrolidineethanamine | HCID 1344 | — |
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | Ethyl 9H-fluorene-9-carboxylate | HCID 596964 | — |
| Product | 9H-Fluorene-9-carboxamide, N-(2-(1-pyrrolidinyl)ethyl)-, hydrochloride (1:1) | HCID 3052191 | — |
Reaction Steps
One mol (238 g) of ethyl 9-fluorene carboxylate is treated with 1.6 mol of 2-amino-ethyl pyrrolidine. Heated for 2 hours at 150° C., the ethanol distills over as it is formed. The reaction mass obtained is dissolved in methylene chloride, washed three times with water, dried, filtered and distilled to dryness.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04192883 |
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| Source dataset | uspto-grants-1980_03 |
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| ORD ID | ord-b9f14a5e0f884673a8a949e97be784dd |
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| Source note | uspto-grants-1980_03 |
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