HuagongsheHuagongshe Chemistry Print Report · For research reference only
L-Lysine → 4-carboxy-2-methylbutanoyl-L-lysine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | L-Lysine | HCID 5962 | — |
| Reactant | benzyl (2S)-2-aminopropanoate | HCID 726858 | — |
| Reactant | benzyl (2S)-2-amino-6-(phenylmethoxycarbonylamino)hexanoate | HCID 7269426 | — |
| Reactant | Nalpha-(4-methoxycarbonyl-2-methylbutanoyl)-L-lysine | HCID 22804617 | — |
| Reactant | Nalpha-(4-methoxycarbonyl-2-methylbutanoyl)-Nepsilon-benzyloxycarbonyl-L-lysine benzyl ester | HCID 86736432 | — |
| Product | 4-carboxy-2-methylbutanoyl-L-lysine | HCID 86736861 | — |
Reaction Steps
By substituting Nε -benzyloxycarbonyl-L-lysine benzyl ester for the L-alanine benzyl ester in the procedure of Example 23 and then treating the product by the procedures of Examples 24 and 26, Nα -(4-methoxycarbonyl-2-methylbutanoyl)-Nε -benzyloxycarbonyl-L-lysine benzyl ester, Nα -(4-methoxycarbonyl-2-methylbutanoyl)-L-lysine and Nα -(4-carboxy)-2-methylbutanoyl)-L-lysine are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04192881 |
| Source dataset | uspto-grants-1980_03 |
| ORD ID | ord-86bf70b7eb4a4004b7aaeba0028bf5f7 |
| Source note | uspto-grants-1980_03 |