HCID 53674511, compound → HCID 70585631, compound

Participants

Reaction Steps

6-Methylpregna-4,6-diene-3,11,20-trione (1.7 g) in ethyl acetate (100 ml) was hydrogenated at atmospheric pressure using 10% palladium on charcoal (500 mg) as catalyst. The catalyst was filtered off and the filtrate evaporated. Crystallisation of the residue from acetonepetroleum ether (b.p. 60°-80°) gave the title compound (720 mg), m.p. 174°-176°, [α]D +106°.

Provenance & Evidence