HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → 1,3-Diphenylpropane-1,3-diamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | 3,5-diphenyl-4,5-dihydro-1H-pyrazole | HCID 3683844 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 1,3-Diphenylpropane-1,3-diamine | HCID 86844 | — |
Reaction Steps
111 g (0.5 mol) of 3,5-diphenyl-2-pyrazoline are hydrogenated with 10 g of freshly prepared Raney nickel in 400 ml of methanol saturated with NH3 for 14 hours at 80° C./100 atmospheres. The catalyst is filtered off and the solvent is removed in a rotary evaporator. Distillation under a high vacuum gives 102 g=90% of theory of a colourless oil1/2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04193905 |
| Source dataset | uspto-grants-1980_03 |
| ORD ID | ord-1e1b7082371e4888a0003e0dfb6368ad |
| Source note | uspto-grants-1980_03 |