HCID 178432449, compound → HCID 12405793, compound

HRID 1701539Notes

Reaction equation

HRID 1701539 reaction equation
OC1C(C)=NC([Br:9])=CN=1.O[C:11]1[C:16]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)=[N:15][C:14]([Br:23])=[CH:13][N:12]=1>>[Br:9][C:11]1[C:16]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)=[N:15][C:14]([Br:23])=[CH:13][N:12]=1

Participants

3

Reactant 2

HCID 178432449HCID 178432449, compoundHCID 178517601HCID 178517601, compound

Product 1

HCID 12405793HCID 12405793, compound

Procedure

By replacing the 2-hydroxy-3-methyl-5-bromopyrazine used in Step A of Preparation 87 by an equivalent quantity of 2-hydroxy-3-phenyl-5-bromopyrazine and following substantially the same procedure there is obtained 2,5-dibromo-3-phenylpyrazine.

Sources & evidence

ORD record
ord-ab3deb2a82eb462b86340c2646a7b60e
Source dataset
uspto-grants-1980_03
Patent number
US04193995

Reaction notes

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