HCID 178432449, compound → 2,5-Dibromo-3-ethylpyrazine

HRID 1701540Notes

Reaction equation

HRID 1701540 reaction equation
OC1C(C)=NC([Br:9])=CN=1.O[C:11]1[C:16]([CH2:17][CH3:18])=[N:15][C:14]([Br:19])=[CH:13][N:12]=1>>[Br:9][C:11]1[C:16]([CH2:17][CH3:18])=[N:15][C:14]([Br:19])=[CH:13][N:12]=1

Participants

3

Reactant 2

HCID 178432449HCID 178432449, compoundHCID 1784375552-Hydroxy-3-ethyl-5-bromopyrazine

Product 1

HCID 205289272,5-Dibromo-3-ethylpyrazine

Procedure

By replacing the 2-hydroxy-3-methyl-5-bromopyrazine used in Step A of Preparation 87 by an equivalent quantity of 2-hydroxy-3-ethyl-5-bromopyrazine and following substantially the same procedure, there is obtained 2,5-dibromo-3-ethylpyrazine.

Sources & evidence

ORD record
ord-46aad5879d3d453fad05d8e63a72e871
Source dataset
uspto-grants-1980_03
Patent number
US04193995

Reaction notes

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