HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenolate Sodium → 2-Amino-3-morpholino-5-phenoxypyrazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenolate Sodium | HCID 4445035 | — |
| Reactant | 5-Bromo-3-morpholinopyrazin-2-amine | HCID 16740441 | — |
| Product | 2-Amino-3-morpholino-5-phenoxypyrazine | HCID 20528948 | — |
Reaction Steps
A suspension of 0.1 mole of sodium phenoxide and 0.1 mole of 2-amino-3-morpholino-5-bromopyrazine is refluxed 10-20 hours. The cooled mixture is extracted with diethyl ether, washed with cold 2 N sodium hydroxide solution, dried and evaporated to give 2-amino-3-morpholino-5-phenoxypyrazine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04193995 |
| Source dataset | uspto-grants-1980_03 |
| ORD ID | ord-332c467193e946e894bbbc4c6ff8eb2f |
| Source note | uspto-grants-1980_03 |