反应详情

A mixture of 3,3-dimethypent-4-enoic acid (18.2 g.), carbon tetrachloride (100 ml.), bromotrichloromethane (57.0 g.) and benzoyl peroxide (0.15 g.) was refluxed under a nitrogen atmosphere for 72 hours after which the volatile portion was removed by evaporation under reduced pressure. The residue was recrystallised from petroleum ether (boiling range 80° to 100° C.) to yield 4-bromo-3,3-dimethyl-6,6,6-trichlorohexanoic acid, m.p. 123°-124° C.

1. temperaturewas refluxed under a nitrogen atmosphere for 72 hours after which the volatile portion
2. customwas removed by evaporation under reduced pressure
3. customThe residue was recrystallised from petroleum ether (boiling range 80° to 100° C.)