Ethylene Oxide → N-decyl-4-(2-hydroxyethoxy)butyramide

Participants

Reaction Steps

In a steel autoclave, 243 grams (1 mole) of N-decyl-4-hydroxybutyramide at a temperature of 130° C. was admixed with 44 grams (1 mole) of oxirane which was added to the autoclave as a compressed gas. The reaction mixture was stirred and autogenous pressure caused a drop in pressure during the reaction. After the reaction was complete in a period of about 2 hours, 281 grams of product were obtained. The product was then cooled to room temperature whereupon a light solid having a melting point of 48° C. was obtained. IR=6.11 mu.

Provenance & Evidence